Journal of Drug Discovery and Research

The Journal of Drug Discovery and Research publishes original research articles, reviews, short communications, case studies, and technical perspectives that explore all facets of drug discovery, pharmaceutical innovation, and therapeutic development. We welcome submissions in a variety of thematic areas, including (but not limited to):

Medicinal Chemistry & Drug Design

• Rational drug design, structure–activity relationships (SAR), and lead optimization
• Synthesis, characterization, and evaluation of novel bioactive compounds
• Natural products, synthetic molecules, and peptide-based therapeutics
• Chemical biology, target identification, and mechanistic studies

Computational & AI-Driven Drug Discovery

• Molecular docking, virtual screening, pharmacophore modeling, and QSAR analyses
• Molecular dynamics simulations and in silico ADMET predictions
• AI/ML-enabled hit identification, de novo drug design, and systems-level modeling

Pharmacology, Toxicology & ADME Studies

• In vitro and in vivo pharmacological evaluations of drug candidates
• Toxicity studies, safety profiling, and dose-response assessments
• Pharmacokinetics (PK), pharmacodynamics (PD), and drug–drug interaction analyses
• Biomarker discovery, target validation, and mechanistic pharmacology

Drug Delivery Systems & Nanopharmaceuticals

• Nanocarriers, liposomes, polymeric nanoparticles, and targeted delivery platforms
• Controlled-release systems, transdermal, mucosal, and inhalation delivery technologies
• Biocompatibility, stability, and performance of advanced delivery systems

Biopharmaceuticals, Biotechnology & Advanced Therapeutics

• Monoclonal antibodies, recombinant proteins, and biosimilars
• Gene therapy, RNA-based therapeutics, and cellular therapies
• Immunotherapy, vaccine development, and engineered biologics

Pharmaceutical Analysis & Quality Assurance

• Analytical method development, validation, and impurity profiling
• Chromatographic, spectroscopic, and mass spectrometric characterization
• Stability studies, quality control, and regulatory compliance
• Analytical approaches for complex and biological formulations

Clinical Research & Translational Drug Development

• Preclinical-to-clinical translation strategies
• Early-phase clinical trials, dose optimization, and therapeutic index assessment
• Precision medicine, personalized therapies, and biomarker-driven clinical studies
• Pharmacovigilance, real-world evidence, and post-marketing evaluations

Natural Products, Traditional Medicines & Bioactive Compounds

• Isolation, characterization, and pharmacological assessment of natural products
• Ethnopharmacology and traditional medicinal systems
• Standardization, quality, and mechanistic insights into natural therapeutics

Emerging, Interdisciplinary & Applied Pharmaceutical Sciences

• Drug repurposing, polypharmacology, and multi-target therapeutics
• Industrial drug development, formulation technologies, and scale-up innovations
• Regulatory science, policy, and ethics in drug research and development
• Intellectual property, commercialization, and technology transfer