Oncology Therapeutics and Drug Development

Prof. Dr. SK. Abdul Rahaman is an accomplished academic leader with over 23 years of teaching and research experience and more than 12 years in higher education administration. He has held key leadership roles including Professor, Principal, Dean, and NAAC/QCI Assessor. His expertise spans accreditation and rankings (NAAC, NBA, NIRF, QS, THE), research governance, international collaborations, and policy development. He has authored 125+ publications, secured ₹1.63 Crores in funded projects, guided 230+ students, and contributed significantly to institutional development and global academic visibility.

• Pharmaceutical Chemistry and Drug Design
• AI/ML applications in healthcare and pharmaceutical sciences
• Clinical research, pharmacovigilance, and translational research
• Biosensors for cancer diagnostics
• Computer-Aided Drug Design (CADD)
• Natural products, herbal and nano-formulations
• Analytical method development (RP-HPLC, LC–MS, HPTLC)
• Synthesis and biological evaluation of heterocyclic compounds

• NAAC Assessor (since 2018) and QCI Assessor

• Organized 130+ national and international conferences/workshops

• Secured and managed government-funded research projects (DST, AICTE, ICMR, CST)

• Established international MoUs with universities in USA, Singapore, Malaysia, Netherlands, and UAE

• Board of Studies Chairperson/Member and academic auditor

• Principal Investigator / Co-PI for multidisciplinary research and innovation projects

1. Sk.A.Rahaman, Y.Rajendra Prasad, Acta Ciencia Indica, Synthesis and antimicrobial activity of Novel Chalcones, Vol.XXXIV C, No.2, 285(2008). ISSN No. 0253-732X

2. S.A.Rahaman, Y.Rajendra Prasad, Int.J.Chem,Sci., Antihistimine activity of newly synthesized Pyrimidines, 6(4), 2038-2044 (2008) ISSN No. 0972-768X (impact factor:0.745)

3. Sk.Abdul Rahaman, Elayaraja arsan, Devala Rao Garikapati., Journal of Pure and Applied Microbiology, Antibacterial activity of various crude extracts of Justicia tranquebariensis, Vol.2(1), 231-233(2008). ISSN No. 0973-7510 (IF-0.16) (SCOPUS)

4. S.A. Rahaman, Y.Rajendra Prasad Antimicrobial activity of newly synthesized pyrimidine derivatives published in journal of chemical and pharmaceutical research (2009). ISSN No: 0975-7384

5. S.K.Abdul Rahaman, Y.Rajemdra Prasad, Int.J.Chem,Sci., Antifungal activity of newly synthesized chalcones, 7(2), 1447-1452(2009) ISSN No. 0972-768X (impact factor:0.376) (SCOPUS)

6. Sk.A.Rahaman, Y.Rajendra Prasad, Phani Kumar, Barath Kumar, Saudi Pharmaceutical Journal, Synthesis and antihistaminic activity of novel pyrimidines.,17,255- 258 (2009). ISSN No. 13190164 (impact factor: 1.6) UGC – 23840 (SCOPUS)

7. S.A.Rahaman, K.Bhuvaneswari, Y.Rajendra Prasad, International Journal of Chem Tech Research,Synthesis and antihistaminic activity of novel pyrazoline derivatives., Vol.2, 16-20,(2010). ISSN No. 0974-4290 (impact factor: 0.537) (SCOPUS)

8. S.A.Rahaman, Y.Rajendra Prasad, K.Phani Kumar, D.Hareesh, Journal of Sciences, Isalmic Republic of Iran, Synthesis and in vitro antibacterial activity of some novel 2-amino-4,6-diaryl pyrimidine derivatives., 22(1): 27-31 (2011) ISSN No. 1735-0328 (impact factor: 0.995) (SCOPUS)

9. S.A.Rahaman, CH.M.M.Prasada Rao,Y.Ragjendra Prasad , P.Gangi Reddy, International Journal of Pharma.Research and Development, RP-HPLC Method of Simultaneous Estimation of Amlodipine Besylate and Metoprolol in Combined Dosage Form., Vol.2 69-76 (2010). ISSN No. 0974-9446

10. Y Rajendra Prasad, SK A Rahaman, P. Ajay Babu, VRK Sri Teja Ayyangar, Journal of Bioinformatics & Research, QSAR analysis of substituted phenyl-piperazine analogs as Histamine H1-receptor antagonists, 1(1): 1-9 (2012). ISSN NO. 2277-3363.

11. Arsan Elayaraja, Sheik Abdul Rahaman, Journal of Pharmaceutical Sciences and Research, Preliminary Phytochemical Investigation and in vitro evaluation of anthelmentic activity of Pergularia Extensa, Vol.4(1):1654-1656 (2012). ISSN NO. 0975-1459 (IF-0.391) (SCOPUS)

12. Arasan Elayaraja, Sheikh Abdul Rahman and J.Jeevan Kumar, Journal of Pharmacy Research, Pharmacognostical study on Whole plant of Scoparia dulcis, 5(2),1221-1223 (2012). ISSN: 0974-6943

13. Arsan Elayaraja, Sheik Abdul Rahaman, Journal of Pharmaceutical Sciences and Research, Evaluation of Anti-Oxidant and in vitro Antioxidant Activity of Various Extracts of Scoparia dulcis L, Vol.4(2), 1724-1727 (2012). ISSN NO. 0975-1459. (IF-0.391) (SCOPUS)

14. Jyothirmayee.M, Srinivasa Reddy. P, Venkata Durga Tulasi.B, Sk.Abdul rahaman. Journal of Pharmacy Research, Method Development And Validation of Simvastatin By Colorimetry Using 3-Methyl-2- Benzothiazolinone Hydra Zone Hydrochloride Monohydrate (MBTH), 5(4),1967-1969 (2012). ISSN:

0974-6943

15. Mohd.Moinuddin, S.A.Rahaman, International journal of Pharmacy and pharmaceutical Sciences, “Development and Validation of A Reverse Phase HPLC Method for Simultaneous Estimation of Rosuvastatin Calcium and Fenofibrate in Tablet Dosage Form” Vol 4, Suppl 3, 150-154 (2012). ISSN0975 – 1491(Impact factor: 0.553) (SCOPUS)

16. S.A.Rahaman, faqruddin and Mohd.Moinuddin, “Synthesis and antimicrobial activity of 1-(2'',4''- dichlorophenyl)-3-(substituted aryl)-2-propene-1 ones” international journal of Life science and Pharma Research, Vol.2/Issue 3/Jul-Sept (2012). ISSN 2250-0480

17. S.A.Rahaman, Ch. M. M. Prasada Rao, Y. Rajendra Prasad, G Eswara Rao, “Design and Synthesis of 1- (3’,5’-bis trifluoromethyl phenyl)-3-(substituted phenyl)-2-propene-1-one as potent antifungal and antibacterial agents” Der Pharma Chemica, 2012, 4(5):1997-2002. ISSN- 0975 - 413X (SCOPUS)

18. Abdul Rahaman*, Arasan Elayaraja, Prem kumar, Kola Phani kumar, “Hepatoprotective activity of hydroalcoholic extract of Scoparia dulcis Linn. against CCl4 induced hepatotoxicity in rats” Asian Pacific Journal of Tropical Biomedicine, 2012, 1-5; ISSN: 2221-1691 (IF-1.22) (SCOPUS)

19. B V D Tulasi*, Ch Lakshmi Devi, Ch Sai Krishna Reddy, S Abdul Rahaman, " Development and Validation of New Analytical Methods for the Estimation of Ritonavir ", Inventi Rapid: Pharm Analysis & Quality Assurance , 2012; ISSN: 0976-3813

20. Pusapati Madan Ranjit, Shaik Abdul Rahaman* Kola PhaniKumar, Yalamanchali Rajendra Prasad, Thotakura Santhipriya, Nissankara rao Lakshmi Sudeepthi; synthesis, Screening And In Vitro Anticancer Activity Of Piperazine Nucleus Containing Novel Chalcones On Different Cell Lines; International Journal of Pharm Tech Research; Vol.5, No.1, 284-293, 2013; ISSN: 0974-4304 (IF-0.47) (SCOPUS)

21. S.A.Rahaman, et al., Method Development and Validation of Valacyclovir Related Compounds G & E in Valacyclovir by RP-HPLC, International journal of Pharmaceutical Analysis (Recent Sciences); Vol.38, Issue.1 1103-1110; ISSN: 2051-2740 (Impact factor: 1.24)

22. S A Rahaman, Venkata S Rao Somisetty, D Dhachinamoorthi, CH M M Prasada Rao; Development and Validation of New Analytical Methods for the Estimation of Risedronate Sodium Hemi-pentahydrate by HPTLC Method Inventi Rapid: Pharm Analysis & Quality Assurance Vol. 2013, Issue 2, 1-4, 2013; ISSN: 0976-3813.

23. SK.A.Rahaman, Mushabbar basha MD*, B.Praveena and M.Srinidhi; Method Development And Validation Of Ondansetron In Bulk And Pharmaceutical Dosage Form By Stability-Indicating RP-HPLC Method: International Journal of PharmTech Research; Vol.5, No.1, 86-98, Jan-Mar 2013. ISSN: 0974-4304. (IF-0.47) (SCOPUS)

24. Venkata S Rao Somisetty, D Dhachinamoorthi, S A Rahaman, CH M M Prasada Rao; Development and Validation Of Newer Analytical Methods For The Estimation of Deferasirox In Bulk and in Tablet Dosage Form By UV Spectroscopy And RP – HPLC: International Journal of Chem Tech Research; Vol.5, No.4, 1861-1868, April-June 2013. ISSN: 0974-4290. (IF-0.37) (SCOPUS)

25. Srilakshmi M*, S.A. Rahaman, K. Shantha kumari; Development and Validation of UV- Spectrophotometric Method for the Estimation of Terconazole in Bulk and Pharmaceutical Dosage Form; Indo American Journal of Pharmaceutical Research; 3(4), 3057-3064, 2013. ISSN NO: 2231-6876.

26. Shaik Abdul Rahamana*, Pusapati Madan Ranjit, Y. Ankamma Chowdary, T. Nagarani, Y.Rajendra Prasad; Synthesis of Piperazine Nucleus Containing Novel Chalcones and Screening of Antimicrobial Activity against Human Pathogens; Indo American Journal of Pharmaceutical Research; 3(6), 4611-4618, 2013. ISSN NO: 2231-6876.

27. Sk. A. Rahaman, M. Srilakshmi*, G.N. Renuka Devi, Sk. Sharmila; Spectrophotometric Determination of Poorly Water Soluble Drug Terconazole Using Hydrotropic Solubilization Technique; Indo American Journal of Pharmaceutical Research; 3(4), 3527-3534, 2013. ISSN NO: 2231-6876.

28. Kiran Kumar Angadi, Ammani Kandru and Abdul Rahaman; Antihyperglycaemic, Antihyper lipidaemic and Antioxidant Assays (In Vivo) Of Nymphaea Pubescens Leaf Extract; International Journal of Pharma and Bio Sciences; 4(2), (B), 624 – 630, 2013. ISSN NO: 0975-6299 (Impact factor: 0.47) (IF-0.35) (SCOPUS)

29. Varanasi S. N. Murthy*, A. Rohini, K. E. Pravallika, A. Prameela Rani and S. A. Rahaman; Development and validation of a novel UV-Visible spectrophomtric method for cytarabine in bulk and Pharmaceutical dosage forms; Der Pharmacia Lettre; 5(4): 51-55, 2013. ISSN: 0975-5071 (IF-0.45) (SCOPUS)

30. Gondu Eswara Rao, S.A. Rahaman, A. Prameela Rani, Ch. M.M. Prasada Rao; Synthesis, Characterization and Antimicrobial Activity of Novel Chalcones from 1-[4-(1H-imidazol-1-yl) Phenyl] Ethanone; Asian J. Research Chem. 6(7): 687-689, 2013. ISSN 0974-4169

31. D Pardha Saradhi, SK Abdul Rahaman, T Sivannarayana, T. Govardhana Charai; A Novel Quantitative Estimation of Poorly water soluble drug Atorvastatin by using Hydrotropic solubilization techniques; World Journal of Pharmaceutical research. 2(6), 2277-2283, 2013. ISSN 2277-7105

32. Prathyusha V, SK Abdul Rahaman, S Revathi, G Renuka; Development and validation of UV spectrophotometric methods for simultaneous estimation of Ciprofloxacin and Tinidazole in tablet dosage form; International Journal of Pharmacy and Industrial Research. 3(3), 295-300, 2013. ISSN 2231-3656

33. S Revathi, S A Rahaman, V. Prathyusha, G Maheswari, M Neeharika; Development and validation of UV spectrophotometric method for the estimation of Fluvoxamine maleate in bulk and Pharmaceutical dosage form; Indo American Journal of Pharmaceutical Research. 3(8), 6373-6380, 2013. ISSN 2231-6876

34. GN Renuka Devi, V Prathyusha, S A Rahaman, K Shanthakumari; Development and validation of UV spectrophotometric method for the estimation of Dexamethasone sodium phosphate in bulk and Pharmaceutical dosage form; Indo American Journal of Pharmaceutical Research. 3(7), 5055-5061, 2013. ISSN 2231-6876

35. K Bhargavi*, S.A.Rahaman, V Ruth Beulah, M Naga Sirisha; Development and Validation of new analytical Method for Simultaneous estimation of Paracetamol and Domperidone by RP-HPLC; Journal of Pharmacy and Molecular Biology. 1(1), 11-22, 2013.

36. Varanasi S. N. Murthy, S. A. Rahaman, A. Rohini, K. E. Pravallika and A. Prameela Rani; Development and validation of a novel UV-Visible spectrophomtric method for cytarabine in bulk and pharmaceutical dosage forms; Der Pharmacia Lettre. 5 (4), 51-55, 2013. ISSN 0975-5071

37. Neeharika.M, K. Shantha kumari, S.A .Rahaman, Maheswari.G, Revathi.S; RP-HPLC Method for Simultaneous Estimation of Clopidogrel Bisulphate and Atorvastatin Calicium in a Capsule Dosage Form; Indo American Journal of Pharmaceutical Research. Vol 3 Issue 9, 2013. ISSN 2231-6876

38. Phani Kumar. K, Shyam Prasad. K, Lakshmi Sudeepthi. N, Ravi Chandra Sekhara Reddy. D, Abdul Rahaman. S, Madan Ranjith. P; In vitro cytotoxic activity of aqueous extract of Delonix elata (L.) gamble (fabaceae) leaves on mcf-7 & hep g-2 cell lines; International Journal of Pharmacology and Toxicology. Vol 2 Issue 2, 70-75, 2014.

39. B.Priyanka, SK.Abdul Rahaman; Validation and stability indicating RP-HPLC method for the simultaneous determination of Oflaxacin, Ornidazole, Clobestesol propionate, Terbenafine hydrochloride, Methyl paraben, Propyl paraben in bulk and Pharmaceutical dosage form; International journal of Pharmacy and Analytical Research 3 (4), 301-318.

40. K.Barghavi, SK.Abdul Rahaman; Visible-Spectrophotometric Determination Of Paracetamol In Bulk and Pharmaceutical Dosage Form; Indo American Journal of Pharmaceutical Research 3 (9), 7075-7080.

41. CMMP Rao, RP Yejella, SA Rehman, SH Basha; Molecular docking based screening of novel designed chalcone series of compounds for their anti-cancer activity targeting EGFR kinase domain; Bioinformation 11(7), 322. (Pub Med)

42. S Munwar, H Roy, SA Rahaman; Antioxidant and Free Radical Scavenging Activity of Citrus Medica; International Journal of Pharma Research and Health Sciences; Volume 3 (4), 2015, 810-816.

43. A Elayaraja, S Muthupandi, M Radhakrishnan, SA Rahaman; In vitro Antioxidant and Antibacterial Activity of Plant Extracts of Pergularia extensa Chiov; International Journal of Pharmacognosy and Phytochemical Research 2015; 7(3); 510-512.

44. Bommadevara Priyanka, Sk. Abdul Rahaman; Validation and stability indicating RP-HPLC method for the simultaneous determination of Oflaxacin, Ornidazole, Clobestesol propionate, Terbenafine hydrochloride, Methyl paraben, Propyl paraben in bulk and pharmaceutical dosage form; International journal of Pharmacy and Analytical Research; 3 (4), 301-318, 2014.

45. S Munwar, H Roy, SA Rahaman; Analgesic and Antidiabetic activity of Citrus Medica Extracts; International Journal of Life and Biosciences; Volume 1 (3), 46-50, 2015.

46. A Elayaraja, SA Rahaman; Anti-anxiety activity of hydro alcoholic extract of Scoparia dulcis Linn. assessed using different experimental anxiety models In rodents; International Journal of Pharmacological Research 5 (3), 62-67, 2015.

47. Khaleel Noorbasha & Sk. Abdul Rahaman; A Validated Stability indicating RP-HPLC Method for Estimation of Aliskiren, Amlodipine and Hydro chlorothiazide in Bulk and Pharmaceutical Dosage Form; International journal of Pharma Sciences; International journal of Pharma Sciences 5 (1), 918-930, 2015.

48. M Sudhakar, P Lavanya, P Deepika, SK Abdul Rahman; Method Development and Validation for Estimation of Anagrelide Hydrochloride Capsules by RP-HPLC in Bulk and Dosage Forms; Indo American Journal of Pharmacy 1(1), 22-27, 2015.

49. Mamillapalli Vani, SK Abdul Rahaman, Avula Prameela Rani; In vivo antiasthmatic studies & phytochemical characterization on the stem extracts of Alternanthera sessilis L. using Guinea pigs model; Journal of Entomology and Zoology Studies 5 (2), 1160-1171, 2017. (PUBMED)

50. N. Khaleel and Sk. Abdul Rahaman; Validated stability indicating RP-HPLC method for simultaneous determination of atorvastatin, fenofibrate and folic acid in bulk and pharmaceutical dosage form; Der Pharmacia Lettre 8 (4), 13-32, 2016.

51. Gondu Eswara Rao, Sk Abdul Rahaman, A Prameela Rani; Insights from molecular modeling, docking and simulation of imidazole nucleus containing chalcones with EGFR kinase domain for improved binding function; Bioinformation. 12(2), 2016. (PUBMED)

52. Rahaman S. A. and Rajendra Prasad Yejella CH. M. M. Prasada Rao; Molecular Modeling and Docking Based Studies of Novel Chalcone Skeleton Based Compounds on Glucosamine-6-Phosphate Synthase Enzyme; International journal of Pharmaceutical Sciences and research. 7(5), 1000-1011, 2016. (ISSN:2320-5148) (SCOPUS)

53. S.A. Rahaman, Lakshmi Prasanna. K, P. Bhavya, Dr. Balaiah Sandyapakula and Dr. Charan Tej. K;

Development and Implementation of Hospital Formulary for Promoting Rational use of Drugs in Tertiary

Care Hospital in Urban Area of Andhra Pradesh; Indo American Journal of Pharmaceutical Research.

7(4), 8341-8348, 2017.

54. S.A. Rahaman, G Eswara Rao & A. Prameela Rani; Synthesis, Characterization and Biological Evolution of Nitrogenous Heterocyclic Ring Containing Chalcones; Int. J. Pharm. Sci. Rev. Res., 43(2), March - April 2017; Article No. 37, Pages: 200-207 (ISSN 0976 – 044X) (IF-0.389) (SCOPUS)

55. Mamillapalli Vani, Sk Abdul Rahaman, Avula Prameela Rani; Antihistaminic and Anticholinergic Studies on the Stem Extracts of Euphorbia Heterophylla L. The International Journal of Applied Biology and Pharmaceutical Technology [IJABPT]. 8(2), 80-88, 2017. (DOAJ, Google Schloar, Thomson Reuters).

56. Mamillapalli Vani, SK Abdul Rahaman, Avula Prameela Rani; In vivo antiasthmatic studies & phytochemical characterization on the stem extracts of Alternanthera sessilis L. using Guinea pigs model; Journal of Entomology and Zoology Studies 5 (2), 1160- 1171, 2017. (Pubmed Indexed, Index Copernicus)

57. S.A. Rahaman, G Eswara Rao & A. Prameela Rani; Synthesis, Characterization and Biological Evolution of Nitrogenous Heterocyclic Ring Containing Chalcones; Int. J. Pharm. Sci. Rev. Res., 43(2), March - April 2017; Article No. 37, Pages: 200-207 (ISSN 0976 – 044X). (Elsevier, Scopus, Index Copernicus, DOAJ)

58. Swapna Goday, SK Abdulrahaman, A Prameelarani; Development and Validation of stability indicating RP-HPLC method for the simultaneous estimation of combination drugs Trifluridine and Tipiracil in bulk and pharmaceutical dosage forms. IMPACT: International Journal of Research in Applied, Natural and Social Sciences5, 2017/2, 93- 104. (UGC Approved).

59. V Swathi, Abdul Rahaman SK, Anjana Male, T Varalakshmi; In-vivo Screening of Analgesic and Antiulcer Activity on Carum carvi Seeds. International Journal of Drug

Development and Research. 9(3), 1/9/2017. (UGC Approved & Index Copernicus)

60. Mamillapalli Vani, SK. Abdul Rahaman, A. Prameela Rani; In Vitro, In Vivo Antiasthmatic Studies of Talinum portulacifolium F. Asian Journal of Pharmaceutics; 11(2), 7/7/2017. (E-ISSN: 1998-409X) (IF – 0.380) (Web of Sciences, Scopus)

61. Dr. Sk. Abdul Rahaman and Dr. Anjana Male V. Swathi*, V. Sathish Kumar; In Vivo Screening of Analgesic and Antiulcer activity on Carum Carvi Seeds. European Journal of Biomedical and Pharmaceutical sciences 4(10), 2017/5/9, 252-262. (Index Copurnicus, Indian citation Index, Directory of Open Access Journal)

62. Mamillapalli Vani, Shaik Abdul Rahaman, Avula Prameela Rani; Detection and Quantification of Major Phytochemical Markers for Standardization of Talinum Portulacifolium, Gomphrena Serrata, Alternanthera Sessilis and Euphorbia Heterophylla by HPLC. Pharmacognosy Journal. 10(3), 2018. (ISSN: 0975-3575) (IF-0.55) (SCOPUS, Index Copurnicus, Elsevier).

63. V Padmaja, A Rahaman, KS Kumari, GS Kumari; Stability Indicating RP-HPLC Method for Simultaneous Estimation of Reserpine, Dihydralazine Sulphate and Hydrochlorothiazide in Bulk and Pharmaceutical Dosage froms. International Journal of ChemTech Research 11 (03), 192-209, 2018. (Index Copurnicus).

64. SK. Abdul Rahaman, Hare Krishna Roy; Box-Behnken Design for Optimization of Formulation Variables for Fast Dissolving Tablet of Urapidil. Asian Journal of Pharmaceutics 12(3), S946-S954, 2018. (SCOPUS).