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Magnitude of Mycobacterium Tuberculosis and its Rifampicin Resistance using Gene Xpert MTB/RIF Assay among Tuberculosis Suspected Patients at Addis Zemen Hospital, Northwest, Ethiopia: Retrospective Study
Research Article - Volume: 1, Issue: 1, 2026 (February)
Magnitude of Mycobacterium Tuberculosis and its Rifampicin Resistance using Gene Xpert MTB/RIF Assay among Tuberculosis Suspected Patients at Addis Zemen Hospital, Northwest, Ethiopia: Retrospective Study Download PDF

Ayenew Berhan1, Bekele Sharew1, Birhanu Getie1, Seble Worku1, Getu Abeje1, Bereket Maru2, Shewaneh Damatie1, Shega Dires1, Tadila Denber1, Birhanu Malede1, Dessie Tegegne1, Teklehaimanot Kiros1 and Andargachew Almaw1*

1Department of Medical Laboratory Science, Debre Tabor University, Debre Tabor, Ethiopia
2Addis Zemen Hospital, Addis Zemen, Ethiopia

*Correspondence to: Andargachew Almaw, Department of Medical Laboratory Science, Debre Tabor University, Debre Tabor, Ethiopia, E-mail:

Received: December 15, 2025; Manuscript No: JMGH-25-8512; Editor Assigned: December 18, 2025; PreQc No: JMGH-25-8512 (PQ); Reviewed: December 20, 2025; Revised: January 12, 2026; Manuscript No: JMGH-25-8512 (R); Published: February 11, 2026.

ABSTRACT

Mycobacterium tuberculosis and drug-resistant tuberculosis are alarmingly increasing infectious diseases worldwide. Tuberculosis is the major cause of morbidity and mortality, especially in developing countries like Ethiopia. However, there is scarcity of data on the magnitude of Mycobacterium tuberculosis and rifampicin resistance using the Xpert-MTB/RIF assay in the study area. Therefore, this study aimed to assess the magnitude of Mycobacterium tuberculosis and rifampicin resistance among TB suspected patients using the GeneXpert assay at Addis Zemen Hospital, North West Ethiopia.

Keywords: Gene Xpert; Magnitude; Tuberculosis; rifampicin resistance; Addis Zemen; Ethiopia

Citation: Almaw A, Berhan A, Sharew B, Getie B, Worku S, Abeje G, et al. (2026). Magnitude of Mycobacterium Tuberculosis and its Rifampicin Resistance using Gene Xpert MTB/RIF Assay among Tuberculosis Suspected Patients at Addis Zemen Hospital, Northwest, Ethiopia: Retrospective Study. J. Microbiome Gut Health. Vol.1 Iss.1, February (2026), pp:1-7.
Copyright: © 2026 Andargachew Almaw, Ayenew Berhan, Bekele Sharew, Birhanu Getie, Seble Worku, Getu Abeje, Bereket Maru, Shewaneh Damatie, Shega Dires, Tadila Denber, Birhanu Malede, Dessie Tegegne, Teklehaimanot Kiros. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.