Journal of Medicinal Chemistry
Indexed In
Journal Highlights
Chiral Drug Synthesis and Stereochemistry
Covalent Inhibitors and Irreversible Drugs
Prodrug Strategies and Design
Radiopharmaceutical Chemistry
Nanotechnology in Drug Development
Chemical Biology Tools in Target Discovery
Drug Repurposing Repositioning
Drug Receptor Interactions
Ligand Based Drug Design
Structure Based Drug Design
Combinatorial Chemistry
Pharmacophores
Lipinskis Rule of Five and Drug Likeness
Isosterism and Bioisosterism
Click Chemistry in Drug Discovery
Asymmetric Synthesis in Drug Development
Biologics and Monoclonal Antibodies
RNA Based Therapeutics
Proteolysis Targeting Chimeras
Green Chemistry in Medicinal Chemistry
Chemoinformatics and Machine Learning
In Vitro and In Vivo Pharmacology
Animal Models in Drug Testing
Transporters in Drug Delivery
Neuropharmacology and Neurochemistry
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Radiopharmaceutical Chemistry
Radiopharmaceutical chemistry focuses on the design, synthesis, and application of radioactive compounds for diagnosis and therapy. These agents combine a biologically active molecule with a radionuclide, enabling targeted imaging or treatment. Commonly used radionuclides include technetium-99m for SPECT and fluorine-18 for PET imaging. Radiopharmaceuticals play a vital role in oncology, cardiology, and neurology by enabling early disease detection and personalized treatment. Therapeutic radiopharmaceuticals, like those using lutetium-177 or iodine-131, deliver localized radiation to diseased tissues. The field requires expertise in radiochemistry, coordination chemistry, and pharmacokinetics. Strict regulatory and safety protocols are followed due to radioactive handling. Radiopharmaceutical chemistry bridges diagnostics and therapeutics, advancing precision medicine.