Journal of Medicinal Chemistry
Indexed In
Journal Highlights
Chiral Drug Synthesis and Stereochemistry
Covalent Inhibitors and Irreversible Drugs
Prodrug Strategies and Design
Radiopharmaceutical Chemistry
Nanotechnology in Drug Development
Chemical Biology Tools in Target Discovery
Drug Repurposing Repositioning
Drug Receptor Interactions
Ligand Based Drug Design
Structure Based Drug Design
Combinatorial Chemistry
Pharmacophores
Lipinskis Rule of Five and Drug Likeness
Isosterism and Bioisosterism
Click Chemistry in Drug Discovery
Asymmetric Synthesis in Drug Development
Biologics and Monoclonal Antibodies
RNA Based Therapeutics
Proteolysis Targeting Chimeras
Green Chemistry in Medicinal Chemistry
Chemoinformatics and Machine Learning
In Vitro and In Vivo Pharmacology
Animal Models in Drug Testing
Transporters in Drug Delivery
Neuropharmacology and Neurochemistry
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Nanotechnology in Drug Development
Nanotechnology in drug development revolutionizes the way drugs are delivered, targeted, and formulated. Nanoscale carriers like liposomes, dendrimers, and polymeric nanoparticles improve drug solubility, stability, and bioavailability. These systems enable controlled and sustained release, reducing dosing frequency and side effects. Nano carriers can be engineered to target specific tissues or cells, enhancing therapeutic precision. This is especially beneficial in cancer, infectious diseases, and neurological disorders. Surface modifications, such as PEGylating, help evade immune detection and prolong circulation time. Nanotechnology also aids in crossing biological barriers like the blood-brain barrier. Overall, it opens new frontiers for personalized and efficient drug therapies.