Journal of Microbiome and Gut Health

Dr. Md. Salimullah is a senior molecular biologist and biotechnologist with over 29 years of research and administrative experience. He currently serves as Chief Scientific Officer at the National Institute of Biotechnology (NIB), Bangladesh, and National Focal Point for Biotechnology under the Ministry of Science and Technology. He earned his Ph.D. from Saitama University, Japan, and has worked extensively in Japan and Bangladesh, including at RIKEN Omics Science Center. His research contributions span molecular biology, functional genomics, biotechnology, drug and vaccine development, with more than 80 publications in reputed international journals including Nature Genetics and Nature Methods.

• Molecular Biology & Biotechnology
• Functional Genomics & Transcriptomics
• Drug Design & Vaccine Development
• Machine Learning in Biomedical Research
• Human Gut Microbiome
• Genetic Variations & Disease Susceptibility
• Bioinformatics & Computational Biology
• DNA Mutation Screening & Diagnostics

• National Focal Point for Biotechnology, Bangladesh

• Former Director General (Additional Charge), NIB

• Liaison Officer (Bangladesh) for ICGEB, Italy

• Principal Investigator of multiple national & international funded research projects

• Participation in international conferences, workshops, and scientific visits across Japan, Europe, Africa, and Asia

• Editorial Board Member of international scientific journals

• PhD and Master’s thesis supervisor

• External examiner for multiple universities

1. Three Characterized Probiotics from Dairy Sources-Weissella confusa (ProY 5.1), Enterococcus lactis (ProY 5.3), and Leuconostoc lactis (RM 2.1)-Exhibit Potential for Antidiarrheal Effects. Ferdous J, Hossain MS, Sarker PK, Bhuia MS, Al Hasan MS, Chowdhury R, Ali MS, Auwal MR, Das KC, Islam MT, Hashem A, Salimullah M (2025). Probiotics Antimicrob Proteins. 2025 Sep 24. doi: 10.1007/s12602-025-10775-0. PMID: 40991099

2. Harnessing animal model and computational experiments to discover antidiabetic compounds in Ficus racemosa. Hossain MU, Rahman ABZN, Hossain MS, Dey S, Chowdhury ZM, Bhattacharjee A, Ahammad I, Hasan MK, Ahmed I, Hosen MB, Das KC, Keya CA, Salimullah M (2025). BMC Complement Med Ther. 2025 Jul 2;25(1):215. doi: 10.1186/s12906-025-04845-7. PMID: 40604816

3. Association of LEPR Gene Polymorphisms With Youth-Onset Diabetes in Bangladesh. Shayedat-Ullah M, Sultana N, Hasan M, Amin USM, Rahman TA, Roy I, Rayhan M, Sutradhar PC, Salimullah M, Hasanat MA (2025). Cureus. 2025 May 23;17(5):e84696. doi: 10.7759/cureus.84696. PMID: 40551902

4. From sequence to significance: A thorough investigation of the distinctive genome features uncovered in C. Werkmanii strain NIB003. Uzzal Hossain M, Khan Tanvir N, Naimur Rahman ABZ, Mahmud Chowdhury Z, Shahadat Hossain M, Dey S, Bhattacharjee A, Ahammad I, Salma Zohora U, Hashem A, Chandra Das K, Ara Keya C, Salimullah M (2025). Gene. 2025 Jan 15;933:148965. doi: 10.1016/j.gene.2024.148965. PMID: 39332601

5. The Unique Capability of Endolysin to Tackle Antibiotic Resistance: Cracking the Barrier. Sabur A, Khan A, Borphukan B, Razzak A, Salimullah M, Khatun M (2025). J Xenobiot. 2025 Jan 25;15(1):19. doi: 10.3390/jox15010019. PMID: 3999736

6. Publisher Correction: A meta-analysis of bulk RNA-seq datasets identifies potential biomarkers and repurposable therapeutics against Alzheimer's disease. Lamisa AB, Ahammad I, Bhattacharjee A, Hossain MU, Ishtiaque A, Chowdhury ZM, Das KC, Salimullah M, Keya CA (2025). Sci Rep. 2025 Feb 11;15(1):5135. doi: 10.1038/s41598-025-87907-7. PMID: 39934199

7. Higher Serum Dipeptidyl Peptidase-4 Activity in Newly Diagnosed Young-Onset Type 2 Diabetes Mellitus. Mahmood T, Rahman H, Jahan S, Sultana N, Hasan M, Hasan MI, Shehab MA, Fariduddin M, Salimullah M, Hasanat MA (2024). Cureus. 2024 Oct 6;16(10):e70968. doi: 10.7759/cureus.70968. PMID: 39507187

8. A meta-analysis of bulk RNA-seq datasets identifies potential biomarkers and repurposable therapeutics against Alzheimer's disease. Lamisa AB, Ahammad I, Bhattacharjee A, Hossain MU, Ishtiaque A, Chowdhury ZM, Das KC, Salimullah M, Keya CA (2024). Sci Rep. 2024 Oct 21;14(1):24717. doi: 10.1038/s41598-024-75431-z. PMID: 39433822

9. An integrated comparative genomics, subtractive proteomics and immunoinformatics framework for the rational design of a Pan-Salmonella multi-epitope vaccine. Bhattacharjee A, Hosen MR, Lamisa AB, Ahammad I, Chowdhury ZM, Jamal TB, Sohag MMH, Hossain MU, Das KC, Keya CA, Salimullah M (2024). PLoS One. 2024 Jul 3;19(7):e0292413. PMID: 38959229

10. AITeQ: a machine learning framework for Alzheimer's prediction using a distinctive five-gene signature. Ahammad I, Lamisa AB, Bhattacharjee A, Jamal TB, Arefin MS, Chowdhury ZM, Hossain MU, Das KC, Keya CA, Salimullah M (2024). Brief Bioinform. 2024 May 23;25(4):bbae291. PMID: 38877887

11. Subtractive genomics study for the identification of therapeutic targets against Cronobacter sakazakii: A threat to infants. Ahammad I, Bushra Lamisa A, Sharmin S, Bhattacharjee A, Mahmud Chowdhury Z, Ahamed T, Uzzal Hossain M, Chandra Das KC, Salimullah M, Ara Keya C (2024). Heliyon. 2024 Apr 25;10(9):e30332. PMID: 38707387

12. Gut microbiome composition reveals the distinctiveness between the Bengali people and the Indigenous ethnicities in Bangladesh. Ahammad I, Bhattacharjee A, Chowdhury ZM, Rahman A, Hossain MU, Dewan G, Talukder S, Das KC, Keya CA, Salimullah M (2024). Commun Biol. 2024 Apr 25;7(1):500. PMID: 38664512

13. Shotgun metagenomics unravels higher antibiotic resistome profile in Bangladeshi gut microbiome. Bhattacharjee A, Jamal TB, Ahammad I, Chowdhury ZM, Rahman A, Dewan G, … Salimullah M (2023). bioRxiv. doi:10.1101/2023.03.02.530749

14. Subtractive genomics study of Xanthomonas oryzae pv. Oryzae reveals repurposable drug candidate for bacterial leaf blight in rice. Ahammad I, Jamal TB, Lamisa AB, Bhattacharjee A, Zinan N, Hasan Chowdhury MZ, Naimul Islam SM, Faruque KMO, Mahmud Chowdhury Z, Uzzal Hossain M, Chandra Das KC, Ara Keya C, Salimullah M (2024). J Genet Eng Biotechnol. PMID: 38494267

15. Identification of repurposable drug targets in Mycoplasma pneumoniae using subtractive genomics, molecular docking and dynamics simulation. Chowdhury ZM, Jamal TB, Ahammad I, Bhattacharjee A, Lamisa AB, Jani JM, Israk MF, Hossain MU, Das KC, Keya CA, Salimullah M (2023). Heliyon. 2023 Nov 4;9(11):e21466. doi: 10.1016/j.heliyon.2023.e21466. PMID: 38034688

16. Type 2 diabetes linked FTO gene variant rs8050136 is significantly associated with gravidity in gestational diabetes in a sample of Bangladeshi women: Meta-analysis and case-control study. Amin USM, Rahman TA, Hasan M, Tofail T, Hasanat MA, Seraj ZI, Salimullah M (2023). PLoS One. 2023 Nov 30;18(11):e0288318. doi: 10.1371/journal.pone.0288318. PMID: 38033012

17. Investigation of pathogenic germline variants in gastric cancer and development of "GasCanBase" database. Hossain MU, Ahammad I, Moniruzzaman M, Akter Lubna M, Bhattacharjee A, Mahmud Chowdhury Z, Ahmed I, Hosen MB, Biswas S, Chandra Das KC, Keya CA, Salimullah M (2023). Cancer Rep (Hoboken). 2023 Dec;6(12):e1906. doi: 10.1002/cnr2.1906. PMID: 37867380

18. Pharmacoinformatics and molecular dynamics simulation approach to identify anti-diarrheal potentials of Centella asiatica (L.) Urb. against Vibrio cholerae. Al-Mamun A, Ahammad I, Ahmed SS, Akter F, Hossain SI, Chowdhury ZM, Bhattacharjee A, Das KC, Keya CA, Salimullah M (2023). J Biomol Struct Dyn. doi: 10.1080/07391102.2023.2191736. PMID: 36927394

19. High risk genetic variants of human insulin receptor substrate 1 (IRS1) infer structural instability and functional interference. Bhattacharjee A, Pranto SMAM, Ahammad I, Chowdhury ZM, Juliana FM, Das KC, Keya CA, Salimullah M (2023). J Biomol Struct Dyn. doi: 10.1080/07391102.2023.2187232. PMID: 36907599

20. Pathogen-driven gene expression patterns lead to a novel approach to the identification of common therapeutic targets. Hossain MU, Ferdous N, Reza MN, Ahammad I, Tiernan Z, Wang Y, O'Hanlon F, Wu Z, Sarker S, Mohiuddin AKM, Das KC, Keya CA, Salimullah M (2022). Sci Rep. 12(1):21070. doi: 10.1038/s41598-022-25102-8. PMID: 36473896

21. Exploration of Streptococcus core genome to reveal druggable targets and novel therapeutics against S. pneumoniae. Chowdhury ZM, Bhattacharjee A, Ahammad I, Hossain MU, Jaber AA, Rahman A, Dev PC, Salimullah M, Keya CA (2022). PLoS One. 17(8):e0272945. PMID: 35980906

22. Virtual screening reveals liquiritigenin as a broad-spectrum inhibitor of SARS-CoV-2 variants of concern: an in silico study. Ahmed SS, Al-Mamun A, Hossain SI, Akter F, Ahammad I, Chowdhury ZM, Salimullah M (2022). J Biomol Struct Dyn. PMID: 35971968

23. Identification of a novel variant of hepatitis B virus isolated from patient co-infected with hepatitis C virus. Shaha M, Majumder S, Hossain MS, Jahan M, Rahmat R, Asma R, Islam MA, Rahman MH, Das KC, Sarker PK, Mahtab MA, Akbar SMF, Salimullah M (2022). Virus Res. 319:198859. PMID: 35809696

24. Sequence variability of CatSper1 and TNP2 gene in indigenous and crossbred cattle in Bangladesh. Jahan N, Wasim M, Rubaya R, Radeen KR, Alim MA, Hossain MMK, Zohora FT, Das KC, Salimullah M, Bhuyan AA, Alam J (2022). Anim Biotechnol. PMID: 35446730

25. Proteome-Based Investigation Identified Potential Drug Repurposable Small Molecules Against Monkeypox Disease. Bhattacharjee A, Ahammad I, Chowdhury ZM, Das KC, Keya CA, Salimullah M (2022). Mol Biotechnol. PMID: 36357534

26. Community Structure and Functional Annotations of the Skin Microbiome in Healthy and Diseased Catfish, Heteropneustes fossilis. Sultana S, Khan MN, Hossain MS, Dai J, Rahman MS, Salimullah M (2022). Front Microbiol. 13:856014. PMID: 35295300

27. Mitochondria-Targeted SmsHSP24.1 Overexpression Stimulates Early Seedling Vigor and Stress Tolerance by Multi-Pathway Transcriptome-Reprogramming. Khatun M, Borphukan B, Alam I, Keya CA, Panditi V, Khan H, Huq S, Reddy MK, Salimullah M (2021). Front Plant Sci. PMID: 34887885

28. Genetic engineering of eggplant (Solanum melongena L.): Progress, controversy and potential. Alam I, Salimullah M (2021). Horticulturae. 7(4):78

29. Novel mutations in NSP-1 and PLPro of SARS-CoV-2 NIB-1 genome mount for effective therapeutics. Hossain MU, Bhattacharjee A, Emon MTH, Chowdhury ZM, Ahammad I, Mosaib MG, Moniruzzaman M, Rahman MH, Islam MN, Ahmed I, Amin MR, Rashed A, Das KC, Keya CA, Salimullah M (2021). J Genet Eng Biotechnol.

30. Insight of druggable cannabinoids against estrogen receptor β in breast cancer. Bhattacharjee A, Hossain MU, Chowdhury ZM, Rahman SA, Bhuyan ZA, Salimullah M, Keya CA (2021). J Biomol Struct Dyn.

31. Effect of gamma radiation on microbial load, physico-chemical and sensory characteristics of common spices for storage. Rahman M, Islam MA, Das KC, Salimullah M, Mollah MZI, Khan RA (2021). J Food Sci Technol.

32. Wave-wise comparative genomic study for revealing the complete scenario and dynamic nature of COVID-19 pandemic in Bangladesh. Ahammad I, Hossain MU, Rahman A, Chowdhury ZM, Bhattacharjee A, Das KC, Keya CA, Salimullah M (2021). PLoS One.

33. Unveiling ancestral relations, host–pathogen interactions and comparative viral miRNA insights of dengue virus serotypes. Rahman A, Susmi TF, Yasmin F, Bhattacharjee A, Hossain MU, Das KC, Keya CA, Salimullah M (2021). Network Modeling Analysis in Health Informatics and Bioinformatics.

34. Comparative genomic study for revealing the complete scenario of COVID-19 pandemic in Bangladesh. Ahammad I, Hossain MU, Rahman A, Chowdhury ZM, Bhattacharjee A, Emon MTH, Das KC, Keya CA, Salimullah M (2020). medRxiv.

35. An improved Agrobacterium mediated transformation and regeneration protocol for successful genetic engineering and genome editing in eggplant. Khatun M, Borphukan B, Alam I, Keya CA, Khan H, Reddy MK, Salimullah M (2022). Scientia Horticulturae.

36. CDKAL1 gene polymorphisms associated with gestational diabetes mellitus. Amin USM, Parvez N, Rahman TA, Hasan MR, Das KC, Jahan S, Hasanat MA, Seraj ZI, Salimullah M (2022). Diabetol Metab Syndr.

37. Protein-protein interactions network model underlines a link between hormonal and neurological disorders. Hossain MU, Ahammad I, Bhattacharjee A, Chowdhury ZM, Rahman A, Rahman TA, Omar TM, Hasan MK, Islam MN, Emon MTH, Das KC, Keya CA, Salimullah M (2022). Informatics in Medicine Unlocked.

38. Clinical manifestations of hospitalized COVID-19 patients in Bangladesh. Shaha M, Islam MA, Huq F, Roy B, Kabir MA, Salimullah M, Al Mahtab M, Akbar SM (2021). Euroasian J Hepatogastroenterol.

39. High-Risk Polymorphisms Associated with the Molecular Function of Human HMGCR Gene. Das KC, Hossain MU, Moniruzzaman M, Salimullah M, Akhteruzzaman S (2021). Research Square.

40. Genomic surveillance of SARS-CoV-2 viruses in Bangladesh. Jahan M, Bhattacharjee A, Rahmat R, Islam SMR, Akhter T, Ahammad I, Hossain MU, Munshi SU, Salimullah M (2021). Microbiol Resour Announc.

41. Isolation and Characterization of Electrogenic Bacteria from Tannery Wastewater. Islam E, Hossain S, Sarker PK, Towhid ST, Salimullah M, Hashem A (2020). Bangladesh Journal of Microbiology.

42. Microbial Fuel Cell Application for Electricity Generation. Saha TC, Protity AT, Zohora FT, Shaha M, Ahmed I, Barua E, Sarker PK, Mukherjee SK, Barua A, Salimullah M, Hashem A (2019). Adv Ind Biotechnol.

43. Coding-Complete Genome Sequence of SARS-CoV-2 Isolate from Bangladesh. Moniruzzaman M, Hossain MU, Islam MN, Rahman MH, Ahmed I, Rahman TA, Bhattacharjee A, Amin MR, Rashed A, Keya CA, Das KC, Salimullah M (2020). Microbiol Resour Announc.

44. Insight of druggable cannabinoids against estrogen receptor β in breast cancer. Bhattacharjee A, Hossain MU, Chowdhury ZM, Rahman SMA, Bhuyan ZA, Salimullah M, Keya CA (2020). J Biomol Struct Dyn.

45. Association of polymorphism in heat shock protein 70 genes with type 2 diabetes. Moniruzzaman M, Ahmed I, Huq S, Mahmud MS, Begum S, Amin USM, Rahman MH, Sarker PK, Hossain MU, Das KC, Salimullah M (2020). Mol Genet Genomic Med.

46. Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate. Shaha M, Sarker PK, Hossain MS, Das KC, Jahan M, Dey SK, Tabassum S, Hashem A, Salimullah M (2018). F1000Res.

47. An Immunopharmacoinformatics Approach in Development of Vaccine and Drug Candidates for West Nile Virus. Hossain MU, Keya CA, Das KC, Hashem A, Omar TM, Khan MA, Rakib-Uz-Zaman SM, Salimullah M (2018). Front Chem.

48. Identification of a novel tri-genotypic recombinant Hepatitis B virus in Bangladesh. Shaha M, Rahman MH, Jahan M, Dey SK, Das KC, Hashem A, Salimullah M (2018). Virus Res.

49. Molecular evolution and genomics of hepatitis B virus subgenotype C2. Shaha M, Chakraborty S, Hossain MS, Hashem A, Salimullah M (2018). VirusDisease.

50. Complete Genome Sequence of a Circulating Hepatitis B Virus Genotype C Strain. Shaha M, Das KC, Hossain MS, Jahan M, Hashem A, Rahman SR, Salimullah M (2018). Genome Announc.

51. First Report of Leaf Spot Disease in Aloe vera Caused by Nigrospora oryzae in Bangladesh. Begum M, Hamza A, Tanny T, Das KC, Mahmud MT, Salimullah M, Alam I (2018). Plant Disease.

52. Pathway based therapeutic targets identification and CampyNIBase database. Hossain MU, Omar TM, Alam I, Das KC, Mohiuddin AKM, Keya CA, Salimullah M (2018). PLoS One.

53. Evaluation of genetic fidelity of in vitro-propagated Aloe vera plants. Khatun MM, Tanny T, Yesmin S, Salimullah M, Alam I (2018). ScienceAsia.

54. Genotyping of κ-casein and β-lactoglobulin genes in native cattle. Akter S, Anower AKMM, Hossain MMK, Alim MA, Jahan N, Bhuyan AA, Salimullah M, Alam J (2020). Anim Biotechnol.

55. Production and characterization of keratinase enzyme by Arthrobacter sp. Barman NC, Zohora FT, Das KC, Mowla MG, Banu NA, Salimullah M, Hashem A (2017). AMB Express.

56. Finding Potential Therapeutic Targets against Shigella flexneri. Hossain MU, Khan MA, Hashem A, Islam MM, Morshed MN, Keya CA, Salimullah M (2016). Front Microbiol.

57. Therapeutics Insight with Inclusive Immunopharmacology of Rotavirus A. Hossain MU, Hashem A, Keya CA, Salimullah M (2016). Front Pharmacol.

58. Linkage between metabolic and age-related disorders using gene network analysis. Hossain MU, Shibly AZ, Omar TM, Zohora FT, Santona US, Hossain MJ, Hosen MS, Keya CA, Salimullah M (2016). Bioinformation.

59. Pharmacophore based drug designing from Gymnema sylvestre. Hossain MU, Khan MA, Rakib-Uz-Zaman SM, Ali MT, Islam MS, Keya CA, Salimullah M (2016). Biomed Res Int.

60. Isolation, Purification and Characterization of an Extracellular Protease. Hashem A, Yesmin S, Pramanik MK, Islam MS, Rahim KA, Salimullah M, Rahman M (2015). Bioresearch Communications.

61. Deep transcriptome profiling of mammalian stem cells. Fort A, Hashimoto K, Yamada D, Salimullah M, et al. (2014). Nature Genetics.

62. Recent Advancements and Challenges in Microbial Bioremediation. Banik S, Das KC, Islam MS, Salimullah M (2013). JSM Biotechnol Bioeng.

63. Suppression of artifacts and barcode bias in transcriptome analyses. Tang DT, Plessy C, Salimullah M, Suzuki AM, et al. (2013). Nucleic Acids Res.

64. NanoCAGE: a high-resolution technique to interrogate transcriptomes. Salimullah M, Mizuho S, Plessy C, Carninci P (2011). Cold Spring Harb Protoc.

65. Novel concept microarray enabling PCR and multistep reactions. Kinoshita Y, Tayama T, Kitamura K, Salimullah M, et al. (2010). BMC Biotechnol.

66. Linking promoters to functional transcripts with nanoCAGE. Plessy C, Bertin N, Takahashi H, Salimullah M, et al. (2010). Nature Methods.

67. Tunable fractionation of nucleic acids. Salimullah M, Kato S, Murata M, et al. (2009). BioTechniques.

68. Systemic in vitro evolution for peptide aptamers. Kitamura K, Yoshida C, Salimullah M, et al. (2009). J Mol Biol.

69. Rapid In Vitro Synthesis of Pico-mole Quantities of Peptides. Kitamura K, Yoshida C, Salimullah M, et al. (2008). Chem Lett.

70. Novel mutation assay based on direct DNA alteration measurement. Futakami M, Salimullah M, Miura T, et al. (2007). J Biochem.

71. Importance of acetylator phenotype in Asian populations. Zaid RB, Nargis M, Neelotpol S, Salimullah M, et al. (2007). Hum Biol.

72. High-throughput three-dimensional gel electrophoresis (4SR). Salimullah M, Mori M, Nishigaki K (2006). Genomics Proteomics Bioinformatics.

73. Efficient SNP analysis using μTGGE and heteroduplex methods. Salimullah M, Hamano K, Tachibana M, Inoue K, Nishigaki K (2005). Cell Mol Biol Lett.

74. Urinary iodine status and thyroid dysfunction in Bangladesh. Hasanat MA, Rumi MA, Alam MN, Ahmed S, Hasan KN, Khan AY, Salimullah M, et al. (2004). BMRC Bull.

75. PCR for early diagnosis of pulmonary tuberculosis. Parvez MA, Hasan KN, Rumi MA, Ahmed S, Salimullah M, et al. (2003). SE Asian J Trop Med Public Health.

76. Predominance of DEN-3 genotype during dengue outbreak. Aziz MM, Hasan KN, Hasanat MA, Siddiqui MA, Salimullah M, et al. (2002). SE Asian J Trop Med Public Health.

77. Status of Antithyroid antibodies in Bangladesh. Hasanat MA, Rumi MAK, Alam MN, Nadim Hasan K, Salimullah M, et al. (2000). Postgrad Med J.

78. Genetic Background of Diabetic and Nondiabetic Sibs. Sayeed MA, Hassan MS, Hasan KN, Salimullah M, et al. (2000). BMRC Bull.

79. Prevalence of HIV among tuberculosis cases in Dhaka. Salimullah M, Tahera Y, Siddique MA, Salam MA, et al. (2000). Trans R Soc Trop Med Hyg.

80. Dopamine-β-Hydroxylase Activity in Malnourished Rats and Humans. Salimullah M, Rahman MK (1998). Bangladesh J Nutr.