Epigenetics in focus explores heritable changes in gene expression that occur without altering the DNA sequence. These changes are regulated by mechanisms such as DNA methylation, histone modification, and non-coding RNAs. Epigenetics plays a vital role in development, cellular differentiation, and adaptation to environmental factors. It also contributes to disease processes, including cancer, neurological disorders, and metabolic conditions. Understanding epigenetic regulation offers new avenues for diagnostics, prognostics, and therapeutic strategies.