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Journal Highlights

Global Chemo Access
Biomarkers in Action
Pediatric Chemo Advances
Chemoimmunotherapy Synergy
Nano-Chemo Innovations
Personalized Cancer Dosing
Next-Gen Chemotherapeutics
Overcoming Drug Resistance

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Overcoming Drug Resistance

Drug resistance poses a major challenge in the treatment of numerous diseases, particularly cancer, infectious diseases, and chronic conditions such as HIV and tuberculosis. It occurs when pathogens or cancer cells adapt to evade the effects of therapeutic agents, leading to treatment failure, disease progression, and increased mortality.

Overcoming drug resistance requires a multifaceted approach that combines insights from molecular biology, genomics, pharmacology, and clinical research. Key strategies include the development of next-generation inhibitors that target resistance mechanisms, combination therapies that prevent escape pathways, and the use of biomarkers to predict and monitor resistance early in treatment.