Journal of Pediatrics Neonatal Biology

Dr. Mario Giordano, born in Naples on November 23, 1989, is a Senior Medical Officer at the Department of Pediatric Cardiology and Intensive Cardiac Care (UTIC) at AORN “Ospedali dei Colli,” Monaldi Hospital, Naples.
He graduated with honors in Medicine and Surgery from the University of Naples “Federico II” and later specialized in Cardiovascular Diseases at the University of Campania “Luigi Vanvitelli,” achieving the highest grade with distinction.
Dr. Giordano’s primary clinical and research focus is on pediatric and congenital interventional cardiology. He has extensive experience in cardiac catheterization procedures in neonates, children, and adults with congenital heart disease, and he actively contributes to national and international research collaborations.

• Pediatric and congenital interventional cardiology
• Neonatal cardiac catheterization
• Percutaneous closure of septal defects (ASD, PFO, VSD)
• Pulmonary valve implantation and right ventricular outflow tract interventions
• Echocardiographic assessment in congenital heart disease

• Active participation in national and international congresses (SICP, AEPC, ANMCO, EuroACHD, ESC)

• Recipient of “Angelo Soro” Award (2017) and “Federico Marsico” Award (2019) for excellence in interventional pediatric cardiology

• Speaker and presenter at multiple international cardiology symposia

• Contributor to monographs, textbooks, and peer-reviewed publications

• Certified provider of Pediatric Advanced Life Support (PALS) and Advanced Cardiovascular Life Support (ACLS)

1. Arterial Duct Stenting in Duct-Dependent Pulmonary Circulation: Is Surgical Shunt Still Worthwhile? Authors: Santoro G, Giordano M, Gaio G, Palladino MT, Iacono C, Russo MG. J Cardiol & Cardiovasc Ther. 2017; 4(5): JOCCT.MS.ID555650.
2. Fate of Duct-Dependent, Discontinuous Pulmonary Arteries After Arterial Duct Stenting Authors: Santoro G, Capozzi G, Giordano M, Gaio G, Palladino MT, Iacono C, Mahmoud HT, Russo MG. Pediatr Cardiol. 2017 Oct; 38(7):1370–1376.
3. News and Updates in Pediatric Cardiology: Review of Literature from 2014 to 2017 Authors: Russo MG, Cirillo A, Giordano M. Prospettive in Pediatria. Oct–Dec 2017; Vol. 47, No. 188, pp. 265–274.
4. Transcatheter Closure of Arterial Duct in Infants < 6 kg: Amplatzer Duct Occluder Type I vs. Amplatzer Duct Occluder II Additional Sizes Authors: Santoro G, Giordano M, Gaio G, Palladino MT, Capozzi G, Iacono C, Russo MG. Pediatr Cardiol. 2018 Mar; 39(3):627–632.
5. Transcatheter Closure of Postsurgical Ruptured Sinus of Valsalva with Amplatzer Duct Occluder II ASTM Device Authors: Capogrosso C, Santoro G, Giordano M, Russo MG.Ann Pediatr Cardiol. 2018 Jan–Apr; 11(1):86–88.
6. Arterial Duct and Pulmonary Arteriovenous Malformations: A Shunt Masking a Shunt Authors: Giordano M, Santoro G, Palladino MT, Russo MG.Ann Pediatr Cardiol. 2018 Jan–Apr; 11(1):89–91.
7. Diagnosis, Management and Treatment of Septic Shock: From Early Diagnosis to Infection Focus ControlAuthors: Liccardo B, Formisano T, D’Andrea A, Giordano M, Martone F, Avitabile V, Bottino R, Golino P.J Emerg Intern Med. 2018; 2(1):19.
8. Neonatal Arrhythmias: Clinical Management and Therapeutic Approach Authors: Russo MG, Giordano M, Cirillo A. SIN Informa – Magazine of the Italian Society of Neonatology. No. 56 – March 2018.
9. Pulmonary Arterial Stenting Complication: Retrieval of a Stent Lost in a Child with Bilateral Glenn Shunt Authors: Giordano M, Gaio G, Cappelli Bigazzi M, Russo MG. J Clin Case Rep. 2018; 8:1171.
10. Patent Foramen Ovale with Complex Anatomy: Comparison of Two Different Devices (Amplatzer Septal Occluder and Amplatzer PFO Occluder 30/35) Authors: Giordano M, Gaio G, Santoro G, Palladino MT, Sarubbi B, Golino P, Russo MG. Int J Cardiol. 2019 Mar 15; 279:47–50.
11. Percutaneous Closure of an Aortopulmonary Window in a Young Adult: A Case Report of Transcatheter Closure with an Occluder Device Authors: Giordano M, Butera G. Eur Heart J Case Rep. 2020 Apr 4; 4(3):1–4.
12. Interventional Cardiac Catheterization in Neonates: Results from a Multicenter Italian Experience Authors: Giordano M, Santoro G, Agnoletti G, Carminati M, Donti A, Guccione P, Marasini M, Milanesi O, Russo MG, Castaldi B, Cheli M, Formigari R, Gaio G, Giugno L, Lunardini A, Pepino C, Spadoni I. Int J Cardiol. 2020 Sep 1; 314:36–42.
13. Interventional Cardiac Catheterization in Neonates: Results from a Multicenter Italian Experience Authors: Giordano M, Santoro G, Agnoletti G, Carminati M, Donti A, Guccione P, Marasini M, Milanesi O, Castaldi B, Cheli M, Formigari R, Gaio G, Giugno L, Lunardini A, Pepino C, Russo MG, Spadoni I. Data Brief. 2020 May 13; 31:105694.
14. A Rare Cause of Massive Hemoptysis in a Child: Bronchial Dieulafoy’s Disease – The First Report of Transcatheter Treatment in Pediatric Age Authors: Giordano M, Cappelli Bigazzi M, Palladino MT, Russo MG. Ann Thorac Med. 2020 Oct–Dec; 15(4):244–246.
15. Transcatheter Closure of Atrial Septal Defect in the Elderly: Early Outcomes and Mid-Term Follow-Up Authors: Giordano M, Gaio G, D’Alto M, Santoro G, Scognamiglio G, Cappelli Bigazzi M, Palladino MT, Sarubbi B, Golino P, Russo MG. Int J Cardiol CHD. 2020 Jul; 1:100058.
16. Response to Fluid Challenge in Patients with Atrial Septal Defect Authors: D'Alto M, Chessa M, Gaio G, Santoro G, Giordano M, Romeo E, Argiento P, Wacker J, D'Aiello F, Sarubbi B, Russo MG, Naeije R, Golino P. Eur Heart J. 2020 Nov 25; 41(Suppl 2): ehaa946.2167.
17. Transcatheter Closure of a Rare Cause of Pre-Tricuspid Left-to-Right Shunt: A “Double” Levoatriocardinal Vein Without Left Heart Obstructive Lesions Authors: Tuccillo A, Giordano M, Gaio G, Carrozza M, Cappelli-Bigazzi M, Morelli C, Ait-Ali L, Festa P, Russo MG. J Cardiol Cases. 2021 Feb 1; 23(2):65–68.
18. Rare Case of Kawasaki Disease with Cardiac Tamponade and Giant Coronary Artery Aneurysms Authors: Vergara A, Monda E, Mautone C, Renon F, Di Masi A, Giordano M, Limongelli G, Calabrò P, Capozzi G, Russo MG. Cardiol Young. 2021 Feb 11:1–2.
19. Unusual Right Ventricular Outflow Tract Obstruction in Dacron Valved Conduits Authors: Giordano M, Boe B, Berman DP, Butera G. Int J Cardiol CHD. 2021 May; 3:100122.
20. Levoatriocardinal Vein: A Comprehensive Interventional Approach Authors: Giordano M, Caputo A, Gaio G, Marzullo R, Carrozza M, Cappelli-Bigazzi M, Palladino MT, Russo MG. Interv Cardiol. 2021 May; 13(3):302–306.
21. Fluid Challenge and Balloon Occlusion Testing in Patients with Atrial Septal Defects Authors: D'Alto M, Constantine A, Chessa M, Santoro G, Gaio G, Giordano M, Romeo E, Argiento P, Wacker J, D'Aiello F, Sarubbi B, Russo MG, Naeije R, Golino P, Dimopoulos K. Heart. 2022 May 12; 108(11):848–854.
22. Transcatheter Closure of Fenestrated Atrial Septal Aneurysm: Feasibility and Long-Term Results Authors: Mahmoud HT, Gaio G, Giordano M, Pizzuto A, Cuman M, Asklany HT, Palladino MT, Russo MG, Santoro G. J Cardiovasc Med (Hagerstown). 2022 Jan; 23(1):49–59.
23. Transcatheter Closure of Fenestrated Atrial Septal Aneurysm in Children: Feasibility and Long-Term Results Authors: Mahmoud HT, Gaio G, Giordano M, Pizzuto A, Cuman M, Abdel Wahab MAK, Palladino MT, Russo MG, Santoro G. Catheter Cardiovasc Interv. 2022 Jun; 99(7):2043–2053.
24. Novel Echocardiographic Score to Predict Duct-Dependency After Percutaneous Relief of Critical Pulmonary Valve Stenosis/Atresia Authors: Giordano M, Santoro G, Gaio G, Cappelli Bigazzi M, Esposito R, Marzullo R, Di Masi A, Palladino MT, Russo MG. Echocardiography. 2022 May; 39(5):724–731.
25. Impact of Pregnancy on the Natural History of Systemic Right Ventricle in Women with Transposition of the Great Arteries Authors: Marzullo R, Ladouceur M, Gaio G, Giordano M, Russo MG, Sarubbi B. Int J Cardiol. 2022 Nov 1; 366:20–24.
26. Advances in Percutaneous Patent Foramen Ovale Closure: From the Procedure to Echocardiographic Guidance Authors: Sperlongano S, Giordano M, Ciccarelli G, Bassi G, Malvezzi Caracciolo D’Aquino M, Del Giudice C, Gaio G, D’Andrea A, Postolache A, Cappelli Bigazzi M, Scognamiglio G, Sarubbi B, Russo MG, Golino P, Lancellotti P. J Clin Med. 2022 Jul 11; 11(14):4001.
27.  Left Cervical and Circumflex Aortic Arch with Aberrant Right Subclavian Artery Arising from a Kommerell Diverticulum: A Rare Vascular Ring Authors: Giordano M, Serrao A, Gaio G, Oppido G, Russo MG. Ann Pediatr Cardiol. 2022 May–Jun; 15(3):291–293.
28. A Rare Cause of Cyanosis in Neonatal Age: Cor Triatriatum Dexter Authors: Caputo A, Giordano M, Iacono C, Oppido G, Russo MG. Ann Pediatr Cardiol. 2022 Jul–Aug; 15(4):429–430.
29. Intracardiac Total Anomalous Pulmonary Venous Return or Septum Primum Malposition? Complete Repair in Left Atrial Isomerism Authors: Montella AP, Petrarcone CG, Giordano M, D'Andrea C, Oppido G. Multimed Man Cardiothorac Surg. 2023 Aug 14; 2023.
30. Outcomes of Transcatheter Pulmonary SAPIEN 3 Valve Implantation: An International Registry Authors: Hascoët S, Bentham JR, Giugno L, Betrián-Blasco P, ... Giordano M, ... (EUROPULMS3 Investigators). Eur Heart J. 2023 Oct 24: ehad663.
31. Feasibility of Using the Antecubital Vein for Right Heart Catheterization in Children and Adults with Congenital Heart Disease: A Retrospective Single-Center Study Authors: Giordano M, Marzullo R, Gaio G, Bigazzi MC, Palladino MT, Della Cioppa N, Gaudieri G, Fabiani D, Sarubbi B, Russo MG. J Invasive Cardiol. 2023 Oct; 35(10).
32. Patent Foramen Ovale Closure with NobleStitch EL System in a Case of Ebstein’s Anomaly After a Failed Device Attempt Authors: Giordano M, Gaio G, Marzullo R, Scognamiglio G, Altobelli I, Russo MG, Sarubbi B. J Cardiovasc Med (Hagerstown). 2024 Jul; 25(7):559–562.
33. Antiarrhythmic Therapy for Narrow QRS Supraventricular Tachyarrhythmias in Newborns and Infants: Potent Tools to Be Handled with Care Authors: Ciriello GD, Sorice D, Orlando A, Papaccioli G, Colonna D, Correra A, Romeo E, Esposito R, De Marco M, Diana V, Giordano M, Barrile LS, Russo MG, Sarubbi B. Indian Pacing Electrophysiol J. 2024 Jul 19; S0972-6292(24)00109-8.
34. Reply to “Usage of NobleStitch EL” Authors: Giordano M, Gaio G, Marzullo R, Scognamiglio G, Altobelli I, Russo MG, Sarubbi B. J Cardiovasc Med (Hagerstown). 2024 Oct; 25(10):757–758.
35. Congenital Absence of the Pericardium: The Swinging Heart Authors: Marzullo R, Capestro A, Cosimo R, Fogante M, Aprile A, Balardi L, Giordano M, Gaio G, Gauderi G, Russo MG, Schicchi N. J Imaging. 2024 Aug 14; 10(8):199.
36. A Rare Case of Paradoxical Embolization Due to an Acquired Extracardiac Right-to-Left Shunt During COVID-19 Infection: Every Street Leads to Heart Authors: Gaudieri G, Giordano M, Marzullo R, Gaio G, Palladino MT, Della Cioppa N, Russo MG. J Cardiol Cases. 2024 Jul 14; 30(4):111–114.
37. Transcatheter Recanalization and Stenting of a Complete Modified Blalock–Taussig–Thomas (BTT) Shunt Obstruction Authors: Giordano M, Gaio G, Marzullo R, Cappelli Bigazzi M, Russo MG. Ann Pediatr Cardiol. 2024 Nov–Dec; 17(6):431–435.
38. The Role of Transesophageal Echocardiography in Interventional Cardiology of Adult Congenital Heart Diseases Authors: Giordano M, Scognamiglio G, Gaio G, Marzullo R, Palma M, Barracano R, Fusco F, Borrelli N, Sperlongano S, Cimmino G, Russo MG, Sarubbi B. J Clin Med. 2025 Feb 7; 14(4):1049.
39. Transcatheter Pulmonary Valve Implantation in Congenital Heart Diseases: Current Advances and Future Perspectives Authors: Giordano M, Marzullo R, Gaio G, Cappelli Bigazzi M, Ciriello GD, Palladino MT, Sarubbi B, Russo MG. Children (Basel). 2025 Apr 24; 12(5):547.
40.  Prevalence, Classification, and Treatment of Residual Shunt After Patent Foramen Ovale Closure Authors: Ujka K, Pizzuto A, Giordano M, Di Muro FM, Gaio G, Russo MG, Sarubbi B, Meucci F, Santoro G.
    EuroIntervention. 2025; 21:e1–e10.